Anion Gap
(Last Updated - 2/27/2008)

-the form below uses the equation:

Anion Gap =

(Na+) - [(Cl-) + (HCo3-)]


Adjusted Anion Gap (Adjusted for Albumin)=

Measured Anion Gap + (2.5 * [4.5 - Albumin (g/dL)])


Serum Na+ (mEq/L):    
Serum Cl- (mEq/L):       
Serum HCo3- (mEq/L): 
Serum Albumin (g/dL):

Adjusted Anion Gap:
(Normal Range: 3-11 mEq/L)



High Anion Gap Metabolic Acidoses:
   -Lactic Acidosis
   -Ketoacidosis
   -ESRD
   -Methanol, Ethylene Glycol or Isopropyl Alcohol Ingestion
   -Salicylate Toxicity

Normal Anion Gap Acidoses:
   -Diarrhea
   -Isotonic Saline Infusion
   -Early Renal Insufficiency
   -Renal Tubular Acidosis (RTA)
   -Acetazolamide
   -Ureteroenterostomy


Delta-Delta Anion Gap:
   -used to determine if there is a metabolic alkalosis on top of an AGap metabolic acidosis
      -Take the calculated AGap and subtract 12 (a normal AGap)
      -Add the difference to the HCO3 level --> should = 24 (a normal HCO3)
      -If > 24 then there is a metabolic alkalosis on top of the AGap metabolic acidosis


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