Anion Gap
(Last Updated - 2/27/2008)
-the form below uses the equation:
Anion Gap =
(Na+) - [(Cl-) + (HCo3-)]
Adjusted Anion Gap (Adjusted for Albumin)=
Measured Anion Gap + (2.5 * [4.5 - Albumin (g/dL)])
High Anion Gap Metabolic Acidoses:
-Lactic Acidosis
-Ketoacidosis
-ESRD
-Methanol, Ethylene Glycol or Isopropyl Alcohol Ingestion
-Salicylate Toxicity
Normal Anion Gap Acidoses:
-Diarrhea
-Isotonic Saline Infusion
-Early Renal Insufficiency
-Renal Tubular Acidosis (RTA)
-Acetazolamide
-Ureteroenterostomy
Delta-Delta Anion Gap:
-used to determine if there is a metabolic alkalosis on top of an AGap metabolic acidosis
-Take the calculated AGap and subtract 12 (a normal AGap)
-Add the difference to the HCO3 level --> should = 24 (a normal HCO3)
-If > 24 then there is a metabolic alkalosis on top of the AGap metabolic acidosis
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